Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1040PFAM: transcriptional coactivator/pterin dehydratase; KEGG: neu:NE0077 pterin-4-alpha-carbinolamine dehydratase. (113 aa)    
Predicted Functional Partners:
Slit_1042
Ste24 endopeptidase; KEGG: neu:NE0076 M48 family peptidase; PFAM: peptidase M48 Ste24p.
  
    0.812
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
       0.793
Slit_1041
KEGG: mei:Msip34_1440 hypothetical protein.
       0.783
orn
Exonuclease RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
       0.631
Slit_1044
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; KEGG: azo:azo1278 EAL/GGDEF/PAS/PAC-domain-containing signalling protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein; PAC repeat-containing protein.
       0.460
Slit_0346
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.403
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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