Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_1053SMART: beta-lactamase domain protein; KEGG: mmb:Mmol_0130 beta-lactamase domain protein. (252 aa)    
Predicted Functional Partners:
Slit_1054
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: mmb:Mmol_0131 diguanylate cyclase/phosphodiesterase; SMART: GGDEF domain containing protein; EAL domain protein.
 
     0.867
Slit_0423
KEGG: dar:Daro_1048 coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; manually curated; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
   
    0.548
Slit_0876
TIGRFAM: hemerythrin-like metal-binding protein; KEGG: azo:azo0535 putative hemerythrin-like protein.
  
    0.496
Slit_1052
KEGG: chu:CHU_3405 hypothetical protein.
       0.492
bamE
SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
       0.483
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
       0.483
Slit_2261
KEGG: dar:Daro_0678 phosphate transport regulator-like protein.
  
    0.430
Slit_0805
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.401
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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