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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Slit_1085PFAM: ammonium transporter; KEGG: rme:Rmet_4750 Rh-like protein/ammonium transporter. (400 aa)    
Predicted Functional Partners:
Slit_0065
PFAM: nitrogen regulatory protein P-II; KEGG: dar:Daro_0053 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 0.987
Slit_1653
PFAM: nitrogen regulatory protein P-II; KEGG: tmz:Tmz1t_1760 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 0.986
Slit_1029
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; KEGG: mag:amb1535 response regulator; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
      0.757
Slit_1582
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; GGDEF domain containing protein; KEGG: pin:Ping_3129 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
      0.752
Slit_0478
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: dar:Daro_3990 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
      0.743
Slit_0115
KEGG: mei:Msip34_2803 glutamate synthase (ferredoxin); PFAM: glutamate synthase; ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein.
 
  
 0.711
Slit_1543
KEGG: app:CAP2UW1_0633 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
 
      0.679
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
     
 0.658
Slit_1708
Sulfate transporter; KEGG: tmz:Tmz1t_1634 sulphate transporter; TIGRFAM: sulfate transporter; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS.
    
 
 0.653
Slit_2811
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; KEGG: mmb:Mmol_0423 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; PAS fold-3 domain protein.
 
      0.637
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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