Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1090PFAM: restriction modification system DNA specificity domain; N-6 DNA methylase; KEGG: cli:Clim_0128 N-6 DNA methylase. (815 aa)    
Predicted Functional Partners:
Slit_1091
KEGG: cph:Cpha266_0896 type III restriction enzyme, res subunit; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicase.
 
 
 0.996
Slit_2435
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.992
Slit_2431
PFAM: filamentation induced by cAMP protein Fic; KEGG: gur:Gura_3598 death-on-curing family protein.
 
    0.942
Slit_2436
PFAM: restriction modification system DNA specificity domain; KEGG: dar:Daro_1307 restriction modification system DNA specificity subunit.
 
 
0.835
Slit_2437
PFAM: N-6 DNA methylase; KEGG: ava:Ava_3498 N-6 DNA methylase.
 
 
0.835
atpF
ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
   
 
 0.798
Slit_1508
KEGG: cyc:PCC7424_0974 hypothetical protein.
  
 
 0.787
Slit_1089
KEGG: cph:Cpha266_0894 hypothetical protein.
       0.773
Slit_2783
KEGG: pfo:Pfl01_4624 hypothetical protein.
  
 
 0.765
Slit_2433
PFAM: restriction endonuclease; DNA topoisomerase type IA zn finger domain protein; KEGG: eba:ebA67 hypothetical protein.
  
 
 0.692
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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