Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1093KEGG: cli:Clim_1572 hypothetical protein. (311 aa)    
Predicted Functional Partners:
Slit_1092
KEGG: mmb:Mmol_1473 hypothetical protein.
       0.678
Slit_1094
Manually curated; PFAM: helix-turn-helix domain protein; KEGG: bcm:Bcenmc03_5052 XRE family transcriptional regulator; SMART: helix-turn-helix domain protein.
       0.543
Slit_1091
KEGG: cph:Cpha266_0896 type III restriction enzyme, res subunit; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicase.
       0.436
Slit_1089
KEGG: cph:Cpha266_0894 hypothetical protein.
       0.414
Slit_1090
PFAM: restriction modification system DNA specificity domain; N-6 DNA methylase; KEGG: cli:Clim_0128 N-6 DNA methylase.
       0.414
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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