Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1116KEGG: dar:Daro_3198 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp. (228 aa)    
Predicted Functional Partners:
Slit_1119
KEGG: tbd:Tbd_2174 hypothetical protein.
    0.765
Slit_1117
PFAM: Hemerythrin HHE cation binding domain protein; KEGG: tbd:Tbd_2172 hypothetical protein.
 
     0.702
Slit_0422
Transcriptional regulator, Crp/Fnr family; Manually curated; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: app:CAP2UW1_2134 transcriptional regulator, Crp/Fnr family; SMART: cyclic nucleotide-binding; regulatory protein Crp.
  
     0.578
Slit_0465
Putative transcriptional regulator, Crp/Fnr family; KEGG: pmy:Pmen_1780 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
     0.548
Slit_1559
TIGRFAM: diguanylate cyclase; PFAM: cyclic nucleotide-binding; GGDEF domain containing protein; KEGG: mgm:Mmc1_1387 cyclic nucleotide-binding protein; SMART: GGDEF domain containing protein.
  
     0.516
Slit_1118
KEGG: tbd:Tbd_2173 hypothetical protein.
       0.506
Slit_2198
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin.
  
 
  0.459
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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