Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_1117PFAM: Hemerythrin HHE cation binding domain protein; KEGG: tbd:Tbd_2172 hypothetical protein. (145 aa)    
Predicted Functional Partners:
Slit_1119
KEGG: tbd:Tbd_2174 hypothetical protein.
 
     0.951
Slit_1118
KEGG: tbd:Tbd_2173 hypothetical protein.
       0.792
Slit_1116
KEGG: dar:Daro_3198 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp.
 
     0.702
Slit_1126
KEGG: tbd:Tbd_0556 iron-sulfur cluster-binding protein.
  
     0.543
Slit_0581
PFAM: Sterol-binding domain protein; KEGG: app:CAP2UW1_0991 hypothetical protein.
  
     0.528
Slit_0424
PFAM: 2-nitropropane dioxygenase NPD; KEGG: azo:azo0323 2-nitropropane dioxygenase.
 
     0.526
Slit_2591
PFAM: TPR repeat-containing protein; KEGG: har:HEAR1937 putative MSHA biogenesis protein MshN.
  
     0.483
Slit_1122
Nitric-oxide reductase; KEGG: dar:Daro_3191 cytochrome c oxidase, subunit I; PFAM: cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.
 
     0.471
Slit_1127
KEGG: mmb:Mmol_1055 von Willebrand factor type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A.
  
     0.437
Slit_0503
KEGG: dar:Daro_0198 hypothetical protein.
  
     0.411
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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