Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1145PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pna:Pnap_2831 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (423 aa)    
Predicted Functional Partners:
Slit_1147
KEGG: tdn:Suden_0619 sulfide-quinone reductase, putative.
 
 
0.960
Slit_1678
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_2477 putative glutamate synthase (NADPH) small subunit.
   
 0.907
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
    
 0.905
Slit_1171
KEGG: dar:Daro_2138 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.902
Slit_1679
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: tbd:Tbd_2478 reductase, iron-sulfur binding subunit, putative.
  
 
 0.901
Slit_1728
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tbd:Tbd_2225 sulfide-quinone reductase.
  
  
 
0.901
Slit_1675
PFAM: Polysulphide reductase NrfD; KEGG: vok:COSY_0784 intracellular sulfur oxidation protein DsrP.
     
  0.900
Slit_1676
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_2475 iron-sulfur cluster protein.
     
  0.900
Slit_1677
KEGG: tbd:Tbd_2476 hypothetical protein.
     
  0.900
Slit_1680
PFAM: Nitrate reductase gamma subunit; KEGG: tbd:Tbd_2479 putative DsrM protein.
     
  0.900
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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