Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1168Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: mag:amb0826 transcriptional regulator. (299 aa)    
Predicted Functional Partners:
Slit_1169
PFAM: protein of unknown function DUF6 transmembrane; KEGG: hna:Hneap_1702 protein of unknown function DUF6 transmembrane.
  
    0.550
Slit_0115
KEGG: mei:Msip34_2803 glutamate synthase (ferredoxin); PFAM: glutamate synthase; ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein.
     
 0.523
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.477
Slit_1166
PFAM: alpha/beta hydrolase fold; KEGG: mpt:Mpe_A0052 hydrolase or acyltransferase-like protein.
     
 0.470
Slit_1167
KEGG: mpt:Mpe_A0051 putative carboxypeptidase; PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A.
       0.464
Slit_2488
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aeh:Mlg_1449 LysR family transcriptional regulator.
  
     0.439
Slit_0301
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: mei:Msip34_0019 transcriptional regulator, LysR family.
  
     0.436
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.407
Slit_1170
PFAM: Protein of unknown function DUF2257; KEGG: mxa:MXAN_6813 hypothetical protein.
       0.402
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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