STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1171KEGG: dar:Daro_2138 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa)    
Predicted Functional Partners:
Slit_2257
KEGG: tbd:Tbd_1162 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
 
 0.987
Slit_0808
Manually curated; TIGRFAM: serine O-acetyltransferase; KEGG: mca:MCA1830 serine acetyltransferase.
 
 0.986
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 0.979
Slit_1032
Sulfite reductase (ferredoxin); KEGG: nmu:Nmul_A1146 nitrite and sulphite reductase 4Fe-4S region; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein.
  
 
 0.947
Slit_1781
PFAM: aminotransferase class I and II; KEGG: mca:MCA1021 aminotransferase, classes I and II.
    
 0.917
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.907
serC-2
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.907
Slit_1787
PFAM: aminotransferase class I and II; KEGG: nmu:Nmul_A1360 aminotransferase, class I and II.
    
 0.905
Slit_1145
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pna:Pnap_2831 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
 0.903
Slit_1728
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tbd:Tbd_2225 sulfide-quinone reductase.
     
 0.903
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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