Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
Slit_1193PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: nmu:Nmul_A0981 binding-protein dependent transport system inner membrane protein. (345 aa)    
Predicted Functional Partners:
potA
Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
 0.999
Slit_1194
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: nmu:Nmul_A0980 binding-protein dependent transport system inner membrane protein.
0.999
Slit_1195
Extracellular solute-binding protein family 1; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.
 
 0.998
Slit_1665
PFAM: extracellular solute-binding protein family 1; KEGG: rfr:Rfer_3242 extracellular solute-binding protein.
 
  
 0.935
Slit_1196
KEGG: rfr:Rfer_0831 ATP-dependent protease, putative.
       0.535
Slit_1191
KEGG: hch:HCH_02709 transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: GntR domain protein; regulatory protein GntR HTH.
       0.469
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
    0.427
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.419
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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