Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1235TIGRFAM: aminoacyl-histidine dipeptidase; KEGG: dar:Daro_1720 peptidase M20C, Xaa-His dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20. (504 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.911
Slit_2519
KEGG: nmu:Nmul_A1961 leucyl aminopeptidase; PFAM: peptidase M17 leucyl aminopeptidase domain protein; Belongs to the peptidase M17 family.
   
 
 0.911
Slit_0100
KEGG: tbd:Tbd_2408 glutamate--cysteine ligase GshA; TIGRFAM: glutamate/cysteine ligase; PFAM: glutamate--cysteine ligase GshA.
     
 0.900
Slit_1781
PFAM: aminotransferase class I and II; KEGG: mca:MCA1021 aminotransferase, classes I and II.
    
 0.812
Slit_1787
PFAM: aminotransferase class I and II; KEGG: nmu:Nmul_A1360 aminotransferase, class I and II.
   
  0.812
Slit_1171
KEGG: dar:Daro_2138 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.806
Slit_0048
PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: mei:Msip34_0582 peptidase M24.
  
 
 0.617
Slit_1236
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: swd:Swoo_4161 diguanylate cyclase; SMART: GGDEF domain containing protein.
       0.550
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.467
Slit_1263
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
    0.460
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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