Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1246PFAM: YaeQ family protein; KEGG: mei:Msip34_2224 YaeQ family protein. (184 aa)    
Predicted Functional Partners:
Slit_2732
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.732
lolB
Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
   
    0.608
Slit_1247
PFAM: major facilitator superfamily MFS_1; KEGG: afw:Anae109_1599 major facilitator transporter.
       0.546
Slit_1280
TIGRFAM: signal peptidase I; KEGG: nmu:Nmul_A1752 peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.
   
    0.505
Slit_2283
TIGRFAM: signal peptidase I; KEGG: cvi:CV_3687 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.
   
    0.505
Slit_2120
KEGG: tbd:Tbd_1918 hypothetical protein; TIGRFAM: FimV N-terminal domain; FimV C-terminal domain; PFAM: Peptidoglycan-binding lysin domain.
   
    0.502
Slit_0185
PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: mca:MCA0496 hypothetical protein.
   
    0.438
Slit_0436
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
    0.431
Slit_0665
PFAM: protein of unknown function DUF45; KEGG: tmz:Tmz1t_0062 protein of unknown function DUF45.
 
    0.402
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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