Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1247PFAM: major facilitator superfamily MFS_1; KEGG: afw:Anae109_1599 major facilitator transporter. (434 aa)    
Predicted Functional Partners:
Slit_1246
PFAM: YaeQ family protein; KEGG: mei:Msip34_2224 YaeQ family protein.
       0.546
Slit_0333
PFAM: FAD linked oxidase domain protein; KEGG: mei:Msip34_2262 FAD linked oxidase domain protein.
 
   
 0.545
Slit_2065
TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase, type II; KEGG: nmu:Nmul_A2192 chorismate mutase; SMART: Chorismate mutase.
   
 
 0.532
Slit_2458
PFAM: Carbohydrate kinase, FGGY-like; KEGG: fal:FRAAL4566 glycerol kinase.
  
  
 0.497
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.472
Slit_1248
Sulfur relay protein, TusE/DsrC/DsvC family; KEGG: rma:Rmag_0881 sulfite reductase, gamma subunit-related protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein.
       0.438
Slit_2442
PFAM: protein of unknown function DUF1458; KEGG: nmu:Nmul_A2249 hypothetical protein.
  
    0.422
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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