Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1271KEGG: dar:Daro_0438 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase. (405 aa)    
Predicted Functional Partners:
Slit_1352
PFAM: protein of unknown function DUF323; KEGG: mag:amb1714 hypothetical protein.
 
    0.882
Slit_0531
PFAM: Protein phosphatase 2C-like; KEGG: dar:Daro_3360 protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein.
 
 0.878
Slit_0402
PFAM: Protein phosphatase 2C-like; KEGG: har:HEAR2127 putative serine/threonine specific protein phosphatase; SMART: protein phosphatase 2C domain protein.
 
 0.840
Slit_1783
KEGG: signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CBS domain containing protein.
 
      0.753
Slit_1270
KEGG: dar:Daro_0439 hypothetical protein.
       0.726
Slit_2071
Adenylate/guanylate cyclase; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: dal:Dalk_1258 adenylate/guanylate cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
      0.711
Slit_1272
Manually curated; KEGG: nmu:Nmul_A1738 hypothetical protein.
       0.709
Slit_1774
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: aha:AHA_3237 GGDEF domain-containing protein; SMART: GGDEF domain containing protein.
 
      0.701
Slit_0532
FHA domain containing protein; KEGG: dar:Daro_3359 forkhead-associated; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
 
 
 
 0.685
Slit_1543
KEGG: app:CAP2UW1_0633 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
 
      0.616
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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