STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1274RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: nmu:Nmul_A1746 RNA polymerase sigma factor RpoE; TIGRFAM: RNA polymerase sigma factor RpoE; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)    
Predicted Functional Partners:
Slit_1275
PFAM: Anti sigma-E protein RseA family protein; KEGG: nmu:Nmul_A1747 anti sigma-E protein RseA.
 
 
 0.968
Slit_1276
PFAM: MucB/RseB family protein; KEGG: nmu:Nmul_A1748 sigma E regulatory protein, MucB/RseB.
 
 
 0.944
Slit_1277
PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: azo:azo1633 putative sigma-E factor regulatory protein RseC.
     
 0.786
Slit_1278
SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: app:CAP2UW1_1545 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.
     
 0.679
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.637
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
    0.626
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.586
Slit_1273
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.571
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.541
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.492
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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