Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1276PFAM: MucB/RseB family protein; KEGG: nmu:Nmul_A1748 sigma E regulatory protein, MucB/RseB. (325 aa)    
Predicted Functional Partners:
Slit_1275
PFAM: Anti sigma-E protein RseA family protein; KEGG: nmu:Nmul_A1747 anti sigma-E protein RseA.
 
 
 0.998
Slit_1277
PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: azo:azo1633 putative sigma-E factor regulatory protein RseC.
  
  
 0.968
Slit_1274
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: nmu:Nmul_A1746 RNA polymerase sigma factor RpoE; TIGRFAM: RNA polymerase sigma factor RpoE; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.945
Slit_0906
PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: hna:Hneap_0704 positive regulator of sigma E, RseC/MucC.
  
  
 0.848
Slit_1278
SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: app:CAP2UW1_1545 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.
  
  
 0.733
Slit_1273
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.569
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
    0.558
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.552
Slit_2756
PFAM: protein of unknown function YGGT; KEGG: nmu:Nmul_A0580 hypothetical protein.
  
     0.552
Slit_1281
KEGG: net:Neut_1779 putative transmembrane protein.
 
     0.537
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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