Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1290KEGG: tgr:Tgr7_0081 two component transcriptional regulator, AraC family; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region. (370 aa)    
Predicted Functional Partners:
Slit_1289
KEGG: tgr:Tgr7_0082 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein.
 
 0.993
Slit_1029
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; KEGG: mag:amb1535 response regulator; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 0.923
Slit_2225
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: azo:azo2059 REC/GGDEF-domain-containing protein; SMART: GGDEF domain containing protein; response regulator receiver.
 
    0.922
Slit_0465
Putative transcriptional regulator, Crp/Fnr family; KEGG: pmy:Pmen_1780 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
    
  0.902
Slit_1220
KEGG: hna:Hneap_1461 putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
    
  0.902
Slit_1242
Putative transcriptional regulator, Crp/Fnr family; KEGG: amr:AM1_2994 cyclic nucleotide-binding protein, putative; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
    
  0.902
Slit_1432
Putative transcriptional regulator, Crp/Fnr family; KEGG: dal:Dalk_2479 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
    
  0.902
Slit_2707
KEGG: hna:Hneap_1461 putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
    
  0.902
Slit_1545
Diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein; GAF domain protein; TIGRFAM: diguanylate cyclase; KEGG: mms:mma_3133 hypothetical protein; PFAM: GGDEF domain containing protein.
 
    0.830
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
 
 0.797
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.