Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1300KEGG: dar:Daro_1978 HDIG; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region. (273 aa)    
Predicted Functional Partners:
Slit_2225
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: azo:azo2059 REC/GGDEF-domain-containing protein; SMART: GGDEF domain containing protein; response regulator receiver.
 
      0.794
Slit_1299
KEGG: rfr:Rfer_1982 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: response regulator receiver; SMART: response regulator receiver.
     0.715
Slit_1301
KEGG: dar:Daro_0970 response regulator receiver; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region.
 
     0.689
Slit_1774
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: aha:AHA_3237 GGDEF domain-containing protein; SMART: GGDEF domain containing protein.
 
      0.663
Slit_1302
Histidine kinase; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: ATP-binding region ATPase domain protein; Hemerythrin HHE cation binding domain protein; KEGG: rfr:Rfer_1978 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
     0.645
Slit_1239
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aav:Aave_4776 diguanylate cyclase; SMART: GGDEF domain containing protein.
 
      0.619
Slit_1298
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; KEGG: drm:Dred_1346 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver.
       0.580
Slit_1545
Diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein; GAF domain protein; TIGRFAM: diguanylate cyclase; KEGG: mms:mma_3133 hypothetical protein; PFAM: GGDEF domain containing protein.
 
      0.525
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.441
Slit_0560
PFAM: MotA/TolQ/ExbB proton channel; KEGG: azo:azo1108 flagellar motor protein.
 
     0.438
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.