Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Slit_1301KEGG: dar:Daro_0970 response regulator receiver; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region. (443 aa)    
Predicted Functional Partners:
Slit_1302
Histidine kinase; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: ATP-binding region ATPase domain protein; Hemerythrin HHE cation binding domain protein; KEGG: rfr:Rfer_1978 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
   0.933
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
 
 0.755
Slit_1783
KEGG: signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CBS domain containing protein.
 
 
 0.753
Slit_2225
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: azo:azo2059 REC/GGDEF-domain-containing protein; SMART: GGDEF domain containing protein; response regulator receiver.
 
    0.738
Slit_0281
KEGG: pcr:Pcryo_1767 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 
 0.724
Slit_1300
KEGG: dar:Daro_1978 HDIG; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region.
 
     0.689
Slit_0585
Multi-sensor hybrid histidine kinase; KEGG: pin:Ping_2140 fused multi-sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; Hpt domain protein.
 
 0.636
Slit_1289
KEGG: tgr:Tgr7_0082 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein.
 
 
 0.630
Slit_1298
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; KEGG: drm:Dred_1346 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver.
  
  
0.621
Slit_0286
Diguanylate phosphodiesterase; KEGG: bba:Bd1971 hypothetical protein; PFAM: EAL domain protein; cyclic nucleotide-binding; SMART: EAL domain protein; cyclic nucleotide-binding.
 
 
 
 0.608
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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