Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
Databases
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[Homology]
Score
Slit_1308PFAM: secretion protein HlyD family protein; KEGG: cbg:CbuG_1202 multidrug resistance protein A. (328 aa)    
Predicted Functional Partners:
Slit_1307
KEGG: hna:Hneap_0659 drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1.
 
 0.983
Slit_1309
KEGG: maq:Maqu_0619 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.
 
  
 0.846
Slit_2000
KEGG: cvi:CV_0433 outer membrane efflux protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein.
 
 
 0.798
Slit_2358
Manually curated; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; KEGG: mms:mma_0285 outer membrane protein, TolC-like; PFAM: outer membrane efflux protein.
 
 
 0.751
Slit_2002
Efflux transporter, RND family, MFP subunit; KEGG: har:HEAR2713 component of acridine efflux pump, AcrA-like; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   
 0.709
Slit_2001
Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: cti:RALTA_A3188 component of acridine efflux pump, multidrug efflux system; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.
 
   
 0.681
Slit_1487
Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.653
Slit_1597
KEGG: pol:Bpro_1022 type I secretion outer membrane protein, TolC; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
 
 
 0.652
Slit_1863
PFAM: outer membrane efflux protein; KEGG: dar:Daro_2263 outer membrane efflux protein.
  
 
 0.638
Slit_1973
KEGG: dar:Daro_2803 outer membrane efflux protein.
  
 
 0.638
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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