Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_1312PFAM: Ankyrin; KEGG: tmz:Tmz1t_3561 ankyrin. (314 aa)    
Predicted Functional Partners:
Slit_1313
KEGG: mag:amb1840 response regulator; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
       0.773
Slit_1165
PFAM: Ankyrin; KEGG: pmx:PERMA_0372 ankyrin domain protein.
  
     0.676
Slit_1314
Diguanylate cyclase; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; KEGG: azo:azo3777 GGDEF family protein; PFAM: GGDEF domain containing protein.
       0.518
Slit_0509
Putative signal transduction protein with EFhand domain; KEGG: reu:Reut_A3217 calcium-binding EF-hand; PFAM: EF-Hand domain; SMART: Calcium-binding EF-hand-containing protein.
    
 0.460
Slit_1052
KEGG: chu:CHU_3405 hypothetical protein.
    
 0.458
Slit_0652
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
   0.449
Slit_1540
KEGG: net:Neut_1809 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
    
 0.442
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.436
Slit_2868
PFAM: Fructosamine/Ketosamine-3-kinase; KEGG: tbd:Tbd_0148 hypothetical protein.
 
      0.434
Slit_2507
KEGG: nmu:Nmul_A0515 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
   
 0.430
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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