STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1332KEGG: nmu:Nmul_A1744 cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein. (317 aa)    
Predicted Functional Partners:
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.580
Slit_1333
PFAM: protein of unknown function DUF599; KEGG: har:HEAR2527 hypothetical protein.
       0.498
Slit_1868
TIGRFAM: copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; YHS domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: sat:SYN_02351 cation transport ATPase; SMART: TRASH domain protein.
 
  
 0.426
Slit_2922
KEGG: lhk:LHK_01972 cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
 
 
 
 0.417
Slit_1330
TIGRFAM: PAS sensor protein; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; response regulator receiver; KEGG: cpo:COPRO5265_0032 sensory box protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region.
       0.403
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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