Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1335PFAM: protein of unknown function DUF347; KEGG: dar:Daro_2299 hypothetical protein. (253 aa)    
Predicted Functional Partners:
Slit_1336
TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); KEGG: glo:Glov_3726 haloacid dehalogenase, type II; PFAM: Haloacid dehalogenase domain protein hydrolase.
       0.620
Slit_1337
KEGG: abo:ABO_0065 hypothetical protein.
       0.537
Slit_2927
PFAM: phosphoesterase; KEGG: mmi:MMAR_1216 acid phosphatase.
  
     0.531
Slit_2208
PFAM: Methyltransferase type 11; KEGG: tbd:Tbd_2330 hypothetical protein.
  
     0.402
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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