Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1344Thioesterase domain protein; KEGG: har:HEAR0065 hypothetical protein; TIGRFAM: thioesterase domain protein; PFAM: Thioesterase putative. (150 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.773
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
  
  
 0.734
Slit_1347
PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: lbf:LBF_3232 NADH:flavin oxidoreductase.
       0.518
Slit_1856
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nmu:Nmul_A0097 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
 
 0.514
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.460
Slit_1343
PFAM: aldo/keto reductase; KEGG: ypb:YPTS_1101 aldo/keto reductase.
     
 0.422
Slit_1348
KEGG: mmb:Mmol_1115 YceI family protein; PFAM: YceI family protein; SMART: YceI family protein; Belongs to the UPF0312 family.
       0.402
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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