Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_1347PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: lbf:LBF_3232 NADH:flavin oxidoreductase. (355 aa)    
Predicted Functional Partners:
Slit_1348
KEGG: mmb:Mmol_1115 YceI family protein; PFAM: YceI family protein; SMART: YceI family protein; Belongs to the UPF0312 family.
       0.597
Slit_1856
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nmu:Nmul_A0097 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
  
 0.546
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
     
 0.543
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
       0.541
Slit_1349
YceI family protein; KEGG: dar:Daro_2795 YceI; PFAM: YceI family protein; SMART: YceI family protein; Belongs to the UPF0312 family.
       0.526
Slit_1344
Thioesterase domain protein; KEGG: har:HEAR0065 hypothetical protein; TIGRFAM: thioesterase domain protein; PFAM: Thioesterase putative.
       0.518
Slit_1350
PFAM: Pirin domain protein; KEGG: azo:azo3369 hypothetical protein; Belongs to the pirin family.
     
 0.514
Slit_0866
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: lch:Lcho_1553 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
  
 0.477
Slit_0338
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: nmu:Nmul_A1959 zinc-containing alcohol dehydrogenase superfamily protein.
  
 0.449
Slit_1343
PFAM: aldo/keto reductase; KEGG: ypb:YPTS_1101 aldo/keto reductase.
  
  
 0.409
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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