Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1348KEGG: mmb:Mmol_1115 YceI family protein; PFAM: YceI family protein; SMART: YceI family protein; Belongs to the UPF0312 family. (188 aa)    
Predicted Functional Partners:
Slit_1349
YceI family protein; KEGG: dar:Daro_2795 YceI; PFAM: YceI family protein; SMART: YceI family protein; Belongs to the UPF0312 family.
 
     0.926
Slit_2051
PFAM: cytochrome B561; KEGG: tau:Tola_0555 cytochrome b561.
 
  
 0.763
Slit_1350
PFAM: Pirin domain protein; KEGG: azo:azo3369 hypothetical protein; Belongs to the pirin family.
     
 0.599
Slit_1347
PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: lbf:LBF_3232 NADH:flavin oxidoreductase.
       0.597
Slit_2245
PFAM: cytochrome B561; KEGG: rso:RSc0199 cytochrome b561 cytochrome transmembrane protein.
 
  
 0.581
Slit_0172
PFAM: cytochrome B561; KEGG: pmy:Pmen_1714 cytochrome b561.
 
  
 0.522
Slit_1351
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rfr:Rfer_0806 LysR family transcriptional regulator.
       0.424
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
       0.422
Slit_1344
Thioesterase domain protein; KEGG: har:HEAR0065 hypothetical protein; TIGRFAM: thioesterase domain protein; PFAM: Thioesterase putative.
       0.402
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.402
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.