Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1365PFAM: Biopolymer transport protein ExbD/TolR; KEGG: nmu:Nmul_A1028 biopolymer transport protein ExbD/TolR. (140 aa)    
Predicted Functional Partners:
Slit_1366
PFAM: MotA/TolQ/ExbB proton channel; KEGG: har:HEAR2492 putative biopolymer transport ExbB-like protein.
 
 
 0.985
tolQ
Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.837
Slit_1389
PFAM: MotA/TolQ/ExbB proton channel; KEGG: pag:PLES_01991 transport protein ExbB.
 
 
 0.831
Slit_0507
TIGRFAM: TonB family protein; KEGG: neu:NE1626 putative TonB protein.
 
 
 0.825
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
  
    0.809
Slit_1388
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.753
Slit_0519
TIGRFAM: protein TolA; KEGG: neu:NE0217 hypothetical protein.
  
 
 0.673
Slit_0518
Protein TolR; Manually curated; TIGRFAM: protein TolR; KEGG: nmu:Nmul_A2716 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR.
  
   
 0.610
Slit_2681
PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: nmu:Nmul_A0628 TonB-dependent receptor.
 
  
 0.582
Slit_1363
PFAM: protein of unknown function DUF343; KEGG: nmu:Nmul_A1027 hypothetical protein; Belongs to the UPF0434 family.
       0.563
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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