Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1366PFAM: MotA/TolQ/ExbB proton channel; KEGG: har:HEAR2492 putative biopolymer transport ExbB-like protein. (201 aa)    
Predicted Functional Partners:
Slit_1365
PFAM: Biopolymer transport protein ExbD/TolR; KEGG: nmu:Nmul_A1028 biopolymer transport protein ExbD/TolR.
 
 
 0.985
Slit_0507
TIGRFAM: TonB family protein; KEGG: neu:NE1626 putative TonB protein.
 
 
 0.897
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
     0.866
Slit_0518
Protein TolR; Manually curated; TIGRFAM: protein TolR; KEGG: nmu:Nmul_A2716 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR.
 
 
 0.816
Slit_1390
PFAM: Biopolymer transport protein ExbD/TolR; KEGG: rme:Rmet_2279 biopolymer transport protein ExbD/TolR.
 
 
 0.764
Slit_0519
TIGRFAM: protein TolA; KEGG: neu:NE0217 hypothetical protein.
 
 
 0.699
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
     0.683
Slit_1388
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.661
Slit_2913
KEGG: tbd:Tbd_2697 type I secretion outer membrane protein, TolC; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
  
     0.615
Slit_0935
KEGG: tbd:Tbd_2697 type I secretion outer membrane protein, TolC; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
  
     0.614
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.