STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1386PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dar:Daro_2955 4Fe-4S ferredoxin, iron-sulfur binding. (351 aa)    
Predicted Functional Partners:
Slit_1384
PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: dar:Daro_2953 TonB-dependent receptor.
 
     0.817
Slit_1385
KEGG: dar:Daro_2954 hypothetical protein.
       0.793
Slit_1387
KEGG: dar:Daro_2956 cytochrome c biogenesis protein, transmembrane region.
       0.793
Slit_1389
PFAM: MotA/TolQ/ExbB proton channel; KEGG: pag:PLES_01991 transport protein ExbB.
  
    0.643
Slit_1388
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
       0.642
Slit_1390
PFAM: Biopolymer transport protein ExbD/TolR; KEGG: rme:Rmet_2279 biopolymer transport protein ExbD/TolR.
       0.633
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.477
Slit_1391
KEGG: mac:MA1988 hypothetical protein.
       0.457
Slit_2643
Polyferredoxin-like protein; KEGG: gbm:Gbem_1233 4Fe-4S ferredoxin, iron-sulfur binding protein.
  
     0.450
Slit_1382
KEGG: bav:BAV1476 phage protein.
       0.434
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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