Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1403PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; KEGG: nmu:Nmul_A2416 hypothetical protein. (330 aa)    
Predicted Functional Partners:
Slit_2099
PFAM: Zinc finger, CHCC-type; KEGG: dar:Daro_3295 hypothetical protein.
  
     0.726
bioC
Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
  
     0.721
Slit_2398
PFAM: Domain of unknown function DUF1841; KEGG: nmu:Nmul_A2703 hypothetical protein.
  
     0.718
Slit_0167
PFAM: protein of unknown function DUF185; KEGG: app:CAP2UW1_0267 protein of unknown function DUF185.
  
     0.696
Slit_1404
KEGG: app:CAP2UW1_2813 cyclic nucleotide-regulated small mechanosensitive ion channel; PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; SMART: cyclic nucleotide-binding.
       0.675
Slit_2220
PFAM: protein of unknown function DUF498; KEGG: cvi:CV_0994 hypothetical protein.
 
     0.620
Slit_1525
PFAM: protein of unknown function DUF177; KEGG: nmu:Nmul_A1069 hypothetical protein.
  
     0.617
Slit_1291
ZipA FtsZ-binding region; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.610
Slit_0063
PFAM: protein of unknown function DUF526; KEGG: mms:mma_0167 hypothetical protein.
  
     0.609
Slit_1275
PFAM: Anti sigma-E protein RseA family protein; KEGG: nmu:Nmul_A1747 anti sigma-E protein RseA.
  
     0.602
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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