STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1404KEGG: app:CAP2UW1_2813 cyclic nucleotide-regulated small mechanosensitive ion channel; PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; SMART: cyclic nucleotide-binding. (512 aa)    
Predicted Functional Partners:
Slit_1403
PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; KEGG: nmu:Nmul_A2416 hypothetical protein.
       0.675
Slit_1242
Putative transcriptional regulator, Crp/Fnr family; KEGG: amr:AM1_2994 cyclic nucleotide-binding protein, putative; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
     0.657
Slit_0050
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 0.639
Slit_2198
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin.
 
 
  0.636
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
       0.571
Slit_0465
Putative transcriptional regulator, Crp/Fnr family; KEGG: pmy:Pmen_1780 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
     0.557
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
   
 
 0.557
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
       0.551
Slit_2097
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: dar:Daro_3414 adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
  0.537
Slit_1240
PFAM: MscS Mechanosensitive ion channel; KEGG: syp:SYNPCC7002_A2738 mechanosensitive ion channel family protein.
  
  
 0.527
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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