Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1430PFAM: Cobyrinic acid ac-diamide synthase; KEGG: mms:mma_0064 chromosome partitioning protein ParA. (255 aa)    
Predicted Functional Partners:
Slit_2989
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: app:CAP2UW1_4360 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
 
 0.931
Slit_2580
KEGG: nmu:Nmul_A0176 cell division FtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: DNA translocase ftsK gamma; AAA ATPase.
  
  
 0.547
Slit_1431
PFAM: protein of unknown function DUF1161; KEGG: pst:PSPTO_0154 hypothetical protein.
  
    0.546
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
  
 0.522
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.476
Slit_1432
Putative transcriptional regulator, Crp/Fnr family; KEGG: dal:Dalk_2479 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
       0.420
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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