STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1437TIGRFAM: squalene synthase HpnC; KEGG: eba:ebA6809 terpenoid synthase-related protein; PFAM: Squalene/phytoene synthase. (271 aa)    
Predicted Functional Partners:
Slit_1435
KEGG: mfa:Mfla_1470 amine oxidase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase.
   
 0.968
Slit_1436
TIGRFAM: squalene synthase HpnD; KEGG: app:CAP2UW1_3259 squalene synthase HpnD; PFAM: Squalene/phytoene synthase.
 
  
0.934
Slit_1608
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; KEGG: dar:Daro_0979 NADH dehydrogenase.
     
 0.817
prmB
protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
     
 0.780
nuoH
NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
 
 0.698
Slit_2180
KEGG: rpf:Rpic12D_1115 MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE.
   
 
 0.652
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
    0.649
Slit_0015
SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: mfa:Mfla_2248 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.643
Slit_1440
Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: mei:Msip34_0931 arsenate reductase and related; Belongs to the ArsC family.
       0.635
Slit_1441
Twitching motility protein; KEGG: dar:Daro_1725 pilus retraction protein PilT; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E.
       0.635
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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