Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1440Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: mei:Msip34_0931 arsenate reductase and related; Belongs to the ArsC family. (115 aa)    
Predicted Functional Partners:
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
 
  
 0.944
Slit_1441
Twitching motility protein; KEGG: dar:Daro_1725 pilus retraction protein PilT; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E.
       0.776
prmB
protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
       0.694
dapD
KEGG: tbd:Tbd_1220 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
  
    0.669
Slit_1443
KEGG: nmu:Nmul_A1850 succinyldiaminopimelate transaminase; TIGRFAM: succinyldiaminopimelate transaminase; PFAM: aminotransferase class I and II.
       0.669
Slit_1435
KEGG: mfa:Mfla_1470 amine oxidase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase.
       0.635
Slit_1436
TIGRFAM: squalene synthase HpnD; KEGG: app:CAP2UW1_3259 squalene synthase HpnD; PFAM: Squalene/phytoene synthase.
       0.635
Slit_1437
TIGRFAM: squalene synthase HpnC; KEGG: eba:ebA6809 terpenoid synthase-related protein; PFAM: Squalene/phytoene synthase.
       0.635
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.606
Slit_0866
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: lch:Lcho_1553 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
     
 0.479
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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