Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1441Twitching motility protein; KEGG: dar:Daro_1725 pilus retraction protein PilT; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E. (389 aa)    
Predicted Functional Partners:
Slit_1440
Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: mei:Msip34_0931 arsenate reductase and related; Belongs to the ArsC family.
       0.776
Slit_2699
PFAM: Type II secretion system F domain; KEGG: mei:Msip34_0586 type II secretion system protein.
  
   
 0.776
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
       0.775
Slit_2607
PFAM: Type II secretion system F domain; KEGG: har:HEAR1952 type IV pilus assembly protein TapC.
  
   
 0.768
Slit_0684
PFAM: Type II secretion system F domain; KEGG: dar:Daro_3408 type II secretion system protein.
  
   
 0.765
Slit_1831
PFAM: Type II secretion system F domain; KEGG: tbd:Tbd_1294 type II secretion system protein F.
  
   
 0.758
Slit_2700
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
   
 0.745
Slit_0497
KEGG: cvi:CV_3812 general secretion pathway protein F; TIGRFAM: general secretion pathway protein F; PFAM: Type II secretion system F domain.
  
   
 0.741
Slit_0108
TIGRFAM: type IV pilus assembly protein PilM; KEGG: dar:Daro_0210 type IV pilus assembly protein PilM.
  
  
 0.687
prmB
protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
       0.646
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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