Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1457PFAM: aldo/keto reductase; KEGG: cya:CYA_0976 aldo/keto reductase Tas. (344 aa)    
Predicted Functional Partners:
Slit_1540
KEGG: net:Neut_1809 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
   
  0.583
Slit_1458
PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: bra:BRADO5603 putative extradiol ring-cleavage dioxygenase.
     
 0.573
Slit_1343
PFAM: aldo/keto reductase; KEGG: ypb:YPTS_1101 aldo/keto reductase.
  
 
 0.497
Slit_1456
Hypothetical protein; KEGG: btl:BALH_0723 enterotoxin/cell wall-binding protein.
       0.483
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
  
 0.477
Slit_1459
PFAM: FIST C domain; domain of unknown function DUF1745; KEGG: dar:Daro_3873 hypothetical protein.
       0.455
Slit_1460
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; KEGG: rfr:Rfer_4055 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; PAS fold domain protein; GGDEF domain containing protein.
       0.455
Slit_1455
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-4 domain protein; GAF domain protein; KEGG: rfr:Rfer_0458 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; GAF domain protein; PAC repeat-containing protein.
       0.413
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.