Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1458PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: bra:BRADO5603 putative extradiol ring-cleavage dioxygenase. (262 aa)    
Predicted Functional Partners:
Slit_2382
Carboxylesterase; KEGG: azo:azo2859 carboxylesterase; PFAM: phospholipase/Carboxylesterase.
      0.698
Slit_1207
Manually curated; PFAM: Sel1 domain protein repeat-containing protein; KEGG: mgm:Mmc1_2003 Sel1 domain-containing protein; SMART: Sel1 domain protein repeat-containing protein.
 
      0.649
Slit_2745
KEGG: rxy:Rxyl_1321 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
      0.647
Slit_1459
PFAM: FIST C domain; domain of unknown function DUF1745; KEGG: dar:Daro_3873 hypothetical protein.
       0.620
Slit_1460
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; KEGG: rfr:Rfer_4055 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; PAS fold domain protein; GGDEF domain containing protein.
       0.620
Slit_1350
PFAM: Pirin domain protein; KEGG: azo:azo3369 hypothetical protein; Belongs to the pirin family.
 
  
 0.582
Slit_1457
PFAM: aldo/keto reductase; KEGG: cya:CYA_0976 aldo/keto reductase Tas.
     
 0.573
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.480
Slit_0828
PFAM: Pirin domain protein; KEGG: ajs:Ajs_1985 pirin domain-containing protein; Belongs to the pirin family.
 
  
 0.456
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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