Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1488KEGG: app:CAP2UW1_1980 efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (397 aa)    
Predicted Functional Partners:
Slit_1490
PFAM: protein of unknown function DUF214; KEGG: mei:Msip34_1219 protein of unknown function DUF214.
 
 0.966
Slit_1487
Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 0.953
Slit_1489
KEGG: sdl:Sdel_1725 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 0.953
Slit_2077
PFAM: protein of unknown function DUF214; KEGG: pin:Ping_3708 ABC transporter permease protein.
 
 0.848
Slit_2078
PFAM: protein of unknown function DUF214; KEGG: app:CAP2UW1_4287 protein of unknown function DUF214.
 
 0.843
Slit_1493
TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: rpi:Rpic_0937 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.727
Slit_1491
PFAM: Uracil-DNA glycosylase superfamily; KEGG: tbd:Tbd_0703 hypothetical protein.
       0.726
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.726
Slit_1597
KEGG: pol:Bpro_1022 type I secretion outer membrane protein, TolC; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
 
 0.701
Slit_2913
KEGG: tbd:Tbd_2697 type I secretion outer membrane protein, TolC; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
 
 0.699
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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