Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1500PFAM: SMC domain protein; KEGG: tmz:Tmz1t_1959 SMC domain protein. (921 aa)    
Predicted Functional Partners:
Slit_1501
KEGG: cvi:CV_0860 hypothetical protein.
       0.788
Slit_1502
KEGG: azo:azo1496 hypothetical protein.
       0.788
prfB
Conserved hypothetical protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.773
Slit_0701
KEGG: nmu:Nmul_A0232 hypothetical protein.
  
     0.684
Slit_0455
PFAM: Sporulation domain protein; KEGG: har:HEAR2989 hypothetical protein.
  
     0.669
Slit_1498
Transcriptional regulator, Crp/Fnr family; KEGG: azo:azo2882 putative transcription regulator, Nnr-type; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; cyclic nucleotide-binding.
 
     0.626
Slit_2611
PFAM: protein of unknown function DUF1058; KEGG: eba:ebA1059 of unknown function.
  
     0.610
Slit_0615
KEGG: neu:NE2077 hypothetical protein.
  
     0.587
ycgR
YcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
  
     0.577
Slit_0621
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: dar:Daro_0787 GGDEF; SMART: GGDEF domain containing protein.
  
     0.570
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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