Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (253 aa)    
Predicted Functional Partners:
Slit_1342
TIGRFAM: lactoylglutathione lyase; KEGG: bpt:Bpet0771 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
 0.971
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.708
Slit_1510
PFAM: Methyltransferase type 11; KEGG: tbd:Tbd_1664 methyl-transferase.
     
 0.655
Slit_2271
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; Autoinducer-binding domain protein; regulatory protein LuxR; GGDEF domain containing protein; KEGG: tau:Tola_0479 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; regulatory protein LuxR.
   
 
 0.642
Slit_1245
KEGG: tbd:Tbd_2499 glutaredoxin-like protein; TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
  
  
 0.578
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
     
 0.574
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
    
 
 0.555
Slit_1145
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pna:Pnap_2831 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
   
 0.541
Slit_1728
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tbd:Tbd_2225 sulfide-quinone reductase.
   
 0.541
Slit_0866
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: lch:Lcho_1553 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
     
 0.475
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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