Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_1514PFAM: HI0933 family protein; KEGG: nmu:Nmul_A2547 hypothetical protein. (391 aa)    
Predicted Functional Partners:
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
       0.778
Slit_1513
PFAM: alpha/beta hydrolase fold; KEGG: cyc:PCC7424_4214 phospholipase/carboxylesterase.
       0.773
Slit_1510
PFAM: Methyltransferase type 11; KEGG: tbd:Tbd_1664 methyl-transferase.
       0.499
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.499
Slit_1518
PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: nmu:Nmul_A0383 adenylate cyclase.
       0.461
Slit_1515
PFAM: LemA family protein; KEGG: nha:Nham_3402 hypothetical protein.
       0.444
Slit_1516
PFAM: protein of unknown function DUF477; KEGG: nmu:Nmul_A2118 hypothetical protein.
       0.444
Slit_1517
PFAM: protein of unknown function DUF477; KEGG: nmu:Nmul_A2117 hypothetical protein.
       0.444
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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