STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1540KEGG: net:Neut_1809 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily. (307 aa)    
Predicted Functional Partners:
Slit_0509
Putative signal transduction protein with EFhand domain; KEGG: reu:Reut_A3217 calcium-binding EF-hand; PFAM: EF-Hand domain; SMART: Calcium-binding EF-hand-containing protein.
    
 0.854
Slit_1937
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mei:Msip34_1664 DNA methylase N-4/N-6 domain protein.
    
 0.843
htpG
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
    
 0.832
Slit_1541
CoA-binding domain protein; KEGG: nmu:Nmul_A1676 GCN5-related N-acetyltransferase; PFAM: CoA-binding domain protein; GCN5-related N-acetyltransferase; SMART: CoA-binding domain protein.
 
     0.832
Slit_0670
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.823
Slit_1103
KEGG: dps:DP2255 hypothetical protein.
    
 0.812
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.796
Slit_1052
KEGG: chu:CHU_3405 hypothetical protein.
    
 
 0.782
atpD-2
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 0.754
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
  0.727
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.