Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_1558KEGG: mar:MAE_21710 hypothetical protein. (183 aa)    
Predicted Functional Partners:
Slit_1559
TIGRFAM: diguanylate cyclase; PFAM: cyclic nucleotide-binding; GGDEF domain containing protein; KEGG: mgm:Mmc1_1387 cyclic nucleotide-binding protein; SMART: GGDEF domain containing protein.
       0.601
Slit_1556
Addiction module toxin, RelE/StbE family; KEGG: eba:ebB67 plasmid stabilization system protein protein; TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system.
       0.456
Slit_1557
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.456
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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