Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
Slit_1579KEGG: ade:Adeh_2181 ABC branched-chain amino acid transporter, fused ATPase and inner-membrane subunits; PFAM: ABC transporter related; inner-membrane translocator; SMART: AAA ATPase; Belongs to the binding-protein-dependent transport system permease family. (888 aa)    
Predicted Functional Partners:
Slit_1580
PFAM: inner-membrane translocator; KEGG: ank:AnaeK_1698 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.999
Slit_1581
PFAM: Extracellular ligand-binding receptor; KEGG: ank:AnaeK_1699 extracellular ligand-binding receptor.
 
 
 0.999
Slit_2691
PFAM: inner-membrane translocator; KEGG: app:CAP2UW1_3611 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
 0.999
Slit_2692
PFAM: Extracellular ligand-binding receptor; KEGG: app:CAP2UW1_3612 extracellular ligand-binding receptor.
 
 
 0.999
Slit_2689
ABC transporter related protein; KEGG: mms:mma_2546 ABC-type branched-chain amino acid transport system ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
0.997
Slit_2690
PFAM: inner-membrane translocator; KEGG: app:CAP2UW1_3610 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
 
0.997
Slit_2687
ABC transporter related protein; KEGG: cvi:CV_1506 leucine/isoleucine/valine transport system ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
0.996
Slit_1812
KEGG: rso:RSc2293 hypothetical protein.
  
  
 0.983
Slit_2021
KEGG: app:CAP2UW1_0304 CBS domain containing membrane protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein.
  
    0.920
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.636
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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