STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheBResponse regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (360 aa)    
Predicted Functional Partners:
Slit_1588
KEGG: mei:Msip34_2712 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: Hpt domain protein; CheW domain protein; ATP-binding region ATPase domain protein.
 
 0.997
Slit_0551
CheA signal transduction histidine kinase; KEGG: azo:azo1462 chemotaxis protein CheA; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein.
 
 0.995
Slit_1586
KEGG: dar:Daro_1143 histidine kinase, HAMP region: chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
 
 0.994
Slit_1585
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
 0.990
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.986
Slit_1591
KEGG: mei:Msip34_2715 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer.
 
 0.986
Slit_0546
TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: csa:Csal_2022 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; SMART: chemotaxis sensory transducer; PAS domain containing protein; PAC repeat-containing protein.
 
 0.982
Slit_0544
KEGG: cvi:CV_2852 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
 
 0.981
Slit_0545
KEGG: dar:Daro_1902 histidine kinase, HAMP region: chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
 
 0.981
Slit_2035
KEGG: app:CAP2UW1_2066 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; type IV pilus assembly PilZ; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
 
 0.981
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.