Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1590KEGG: two-component system sensor histidine kinase/response regulator, putative; PFAM: response regulator receiver; SMART: response regulator receiver. (122 aa)    
Predicted Functional Partners:
Slit_1588
KEGG: mei:Msip34_2712 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: Hpt domain protein; CheW domain protein; ATP-binding region ATPase domain protein.
 0.992
Slit_1591
KEGG: mei:Msip34_2715 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer.
 
  0.964
Slit_0551
CheA signal transduction histidine kinase; KEGG: azo:azo1462 chemotaxis protein CheA; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein.
 
 0.957
Slit_1587
KEGG: dar:Daro_1144 CheW-like protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 
 0.950
Slit_1586
KEGG: dar:Daro_1143 histidine kinase, HAMP region: chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
 
  0.941
Slit_0550
Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
 
 
 0.923
Slit_0549
KEGG: dze:Dd1591_1545 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 
 
0.920
Slit_0590
KEGG: tbd:Tbd_1608 flagellar motor switch/type III secretory pathway protein FliN; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein.
   
 0.906
Slit_1589
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mei:Msip34_2713 anti-sigma-factor antagonist.
 
  
 0.902
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
 
 
0.866
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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