Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1595KEGG: hypothetical protein. (180 aa)    
Predicted Functional Partners:
Slit_1596
PFAM: sodium/calcium exchanger membrane region; KEGG: ote:Oter_0016 hypothetical protein.
       0.529
Slit_1593
KEGG: bph:Bphy_6558 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
       0.406
Slit_1594
Multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain protein; TIGRFAM: PAS sensor protein; KEGG: bpy:Bphyt_6241 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase HAMP region domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region.
       0.406
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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