STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1611PFAM: nickel-dependent hydrogenase large subunit; KEGG: nmu:Nmul_A1673 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (495 aa)    
Predicted Functional Partners:
Slit_1610
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: app:CAP2UW1_0999 hydrogen dehydrogenase.
 
 
 0.989
Slit_1608
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; KEGG: dar:Daro_0979 NADH dehydrogenase.
 
 
 
 0.982
Slit_1612
TIGRFAM: hydrogenase maturation protease; KEGG: tmz:Tmz1t_2251 hydrogenase maturation protease.
 
  
 0.960
Slit_1609
PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; KEGG: azo:azo1413 hydrogen dehydrogenase, gamma subunit.
 
   
 0.912
Slit_2422
Hydrogenase assembly chaperone hypC/hupF; KEGG: dar:Daro_3967 hydrogenase expression/formation protein (HUPF/HYPC); TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
   
 0.582
Slit_2419
KEGG: app:CAP2UW1_0735 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
   
 0.565
Slit_1622
Hydrogenase maturation protease; KEGG: tbd:Tbd_1380 peptidase M52, hydrogen uptake protein; TIGRFAM: hydrogenase maturation protease; hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); peptidase M52 hydrogen uptake protein.
  
  
 0.552
Slit_2421
KEGG: rfr:Rfer_4099 hydrogenase expression/formation protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family.
 
   
 0.537
Slit_2423
(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.532
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
     
 0.527
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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