Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1616Manually curated; TIGRFAM: addiction module killer protein; KEGG: cpb:Cphamn1_0569 addiction module killer protein; PFAM: protein of unknown function DUF891. (96 aa)    
Predicted Functional Partners:
Slit_1615
TIGRFAM: addiction module antidote protein; PFAM: helix-turn-helix domain protein; KEGG: noc:Noc_0569 Cro/CI family transcriptional regulator; SMART: helix-turn-helix domain protein.
 
    0.948
Slit_1767
TIGRFAM: addiction module antidote protein; KEGG: bam:Bamb_5333 putative transcriptional regulator.
 
    0.780
Slit_2790
TIGRFAM: addiction module antidote protein; KEGG: bcj:BCAM0626 putative DNA-binding protein.
 
    0.780
Slit_1614
KEGG: azo:azo2664 hypothetical protein.
       0.504
Slit_1617
PFAM: nickel-dependent hydrogenase large subunit; KEGG: tbd:Tbd_1375 Ni-Fe hydrogenase large chain; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
       0.446
Slit_1618
Hypothetical protein; KEGG: cch:Cag_1072 sialic acid synthase.
       0.443
Slit_1619
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_1376 heterodisulfide reductase.
       0.443
Slit_1620
KEGG: tbd:Tbd_1377 hypothetical protein.
       0.428
Slit_1621
TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: tbd:Tbd_1378 Ni-Fe hydrogenase, small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
       0.428
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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